I can't really see "Shackler's" being played on the radio at all.  The classic rock stations won't touch it.  And alternative rock won't play it because it's Guns n Roses.  I don't think that will hurt album sales though.   The single is pretty much dead unless you are Kate Perry or one of those other one hit wonders.  I think Chinese Democracy will sell well no matter what the lead off single is. 

Even though "SR" is a great song.  It doesn't have the widespread appeal like GnR's other hits.  I remember when "You Could Be Mine" came out in 91.  The radio was all over that song.  Because it was heavy yet commercial.  "Shackler's" is more of an acquired taste.  It's definitely not mainstream.  But I still think that even after all this time is a CD is finally released that says "Guns n Roses: Chinese Democracy" it will fly out of the stores.  Just because the media's going to jump all over it and hype the shit out of the release.  Of course I don't know if Axl's ever going to pull the trigger and actually release the damn album.  If the media ever issues a ban on reporting "Chinese Democracy album news" he's screwed.